Medical Weight Loss Singapore: GLP-1 Injections (Wegovy, Saxenda, Mounjaro)

Medical Weight Loss Singapore: GLP-1 Injections

Wegovy, Saxenda, and Mounjaro are prescription-only medications with robust clinical evidence showing weight loss of 15-22% of body weight. In Singapore, access to these treatments is available through licensed medical clinics, including Noah's telehealth platform.

What Are GLP-1 Receptor Agonists?

GLP-1 (glucagon-like peptide-1) receptor agonists were originally developed for type 2 diabetes management. GLP-1 is a hormone naturally released by the gut after eating. It stimulates insulin secretion, suppresses glucagon, slows gastric emptying, and acts on the hypothalamus to reduce appetite and food cravings.

The Three Main GLP-1 Medications Available in Singapore

Wegovy (Semaglutide 2.4 mg Weekly Injection)

Wegovy is administered as a once-weekly subcutaneous injection. The STEP 1 trial found semaglutide 2.4 mg produced mean weight loss of 14.9% of body weight over 68 weeks.

Saxenda (Liraglutide 3 mg Daily Injection)

Saxenda is administered as a once-daily subcutaneous injection. The SCALE Obesity trial demonstrated mean weight loss of 8.0% of body weight over 56 weeks.

Mounjaro (Tirzepatide - Dual GIP/GLP-1 Agonist)

Mounjaro targets two gut hormone receptors - GLP-1 and GIP. The SURMOUNT-1 trial showed mean weight loss of up to 20.9% of body weight at the 15 mg dose over 72 weeks.

Who Qualifies for GLP-1 Weight Loss Treatment?

GLP-1 medications for weight management are indicated for:

• BMI of 30 kg/m2 or higher, or
• BMI of 27 kg/m2 or higher with at least one weight-related comorbidity

A full medical assessment is essential before starting any GLP-1 medication.

Side Effects and What to Expect

The most common side effects are gastrointestinal and occur during dose escalation: nausea, vomiting, diarrhoea or constipation. These typically improve within a few weeks.

Accessing GLP-1 Weight Loss Treatment at Noah Singapore

1. Complete your online health evaluation
2. Consultation with a licensed Singapore doctor
3. Prescription issued if clinically appropriate
4. Ongoing monitoring and dosing adjustments

Start your online evaluation

Noah is a licensed telehealth clinic in Singapore. All consultations are conducted by SMC-registered doctors.